The next VanBUG event is on next Thursday, April 10th at 6pm. Dr. Dana Pe’er will give a presentation titled:
“Revealing heterogeneity between and within tumors”
Abstract:
“Systematic characterization of cancer genomes has revealed a staggering complexity and heterogeneity of aberrations among individuals. More recently appreciated that intra-tumor heterogeneity is of critical importance, each tumor harboring sub-populations that vary in clinically important phenotypes such as drug sensitivity. A major challenge involves the development of analysis methods to integrate the flood of high-throughput data on tumors towards a past of personalized care. We will elaborate on two computational approaches on this path: (1) Integration of genetic and genomic data to identify genetic determinants of cancer. (2) Single cell analysis of signaling based on mass cytometry, a novel technology that can accurately measure more than forty signaling molecules simultaneously single cells.”
Dana Pe’er is an associate professor in the Departments of Biological Sciences and Systems Biology, Columbia University. Our team develops computational methods that integrate diverse high-throughput data to provide a holistic, systems-level view of molecular networks. Currently we have two key focuses: developing computational methods to interpret single cell data and understand cellular heterogeneity; Modeling how genetic and epigenetic variation alters regulatory network function and subsequently phenotype in health and disease. This path has led us to explore how systems biology approaches can be used to personalize cancer care. Dana is recipient of the Burroughs Wellcome Fund Career Award, NIH Directors New Innovator Award, NSF CAREER award, Stand Up To Cancer Innovative Research Grant and a Packard Fellow in Science and Engineering.
Dr. Pe’er’s talk will be proceed by a 10 min introductory talk by Emilia Lim, PhD Candidate, Marra Lab, BC Cancer Research Centre.
Title: to be announced
The other speakers for this year are as follow (save the dates!):
May 1st, 2014 (TBD) – Martin Kryzywinski, Scientist, Canada’s Michael Smith Genome Sciences Centre
Seminar is followed by complementary pizza, refreshments and great networking.
For updates on seminar topics and abstracts, please check out our website at http://vanbug.org.
Please note:
Trainees are invited to meet with the VanBUG speaker for open discussion
of both science and career paths. This takes place 4:30-5:30pm in either
the Boardroom or Lunchroom on the ground floor of the BCCRC
Location:
675 West 10th Avenue
Gordon and Leslie Diamond Family Theatre
BC Cancer Agency
Date/Time:
April 10, 2014
Start Time: 6:00 PM
End Time: 7:30 PM (followed by pizza and drinks)
Contact Name:
William Hsiao
dev@vanbug.org
http://vanbug.org
Regards,
William Hsiao
on behalf of VanBUG Organization Team:
Cedric Chauve (Department of Mathematics, SFU)
Bhavjinder Dhillon (Brinkman Lab, SFU)
Rodrigo Goya (Canada’s Michael Smith Genome Sciences Centre & Centre for High-Throughput Biology, UBC)
William Hsiao (BCCDC Public Health Microbiology & Reference Laboratory)
Kieran O’Neill (BC Cancer Agency)
Raunak Shrestha (Collin’s Lab, Vancouver Prostate Centre)
Shing Hei Zhan (Canada’s Michael Smith Genome Sciences Centre)
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